Departamento de inmunología, facultad de química/ciencias.
Producción Científica
2022
● “Unraveling post-translational modifications in Echinococcus granulosus sensu lato”. Miles S, Magnone J, García-Luna J, Dematteis S, Mourglia-Ettlin G. Acta Trop. 2022 Mar 15;230:106410.
● “Functionalization of Magnetic Beads with Biotinylated Nanobodies for MALDI-TOF/MS-Based Quantitation of Small Analytes”. Lassabe G, Pírez-Schirmer M, González-Sapienza G. Methods Mol Biol. 2022;2446:531-546.
● “Ready-to-use” immunosensor for the detection of small molecules with fast readout. Ding Y, Cui P, Chen H, Li J, Huang L, González-Sapienza G, Hammock BD, Wang M, Hua X. Biosens Bioelectron. 2022 Apr 1;201:113968.
● “Bispecific Single-Domain Antibodies as Highly Standardized Synthetic Calibrators for Immunodiagnosis” (2022). Paula Segovia-de Los Santos, Pedro Quintero-Campos, Sergi Morais, Cesar Echaides, Ángel Maquieira, Gabriel Lassabe, Gualberto Gonzalez-Sapienza. Anal. Chem. 18;94(2):1342-1349.
2021
● “Development of anti-human IgM nanobodies as universal reagents for general immunodiagnostics” (2021) Martina Scarrone , Andrés González-Techera, Romina Alvez-Rosado, Triana Delfin-Riela, Álvaro Modernell, Gualberto González-Sapienza, Gabriel Lassabe. New Biotechnology 64:9-16.
● “Expression and distribution of glutathione transferases in protoscoleces of Echinococcus granulosus sensu lato” (2021) Paula Arbildi, Silvana La-Rocca, Alejandra Kun, Karina R Lorenzatto, Karina M Monteiro, Arnaldo Zaha, Gustavo Mourglia-Ettlin, Henrique B Ferreira, Verónica Fernández. Acta Tropica 221:105991.
● Induction of antigen-specific tolerance by nanobody-antigen adducts that target class-II major histocompatibility complexes. Pishesha N, Harmand T, Smeding LY, Ma W, Ludwig LS, Janssen R, Islam A, Xie YJ, Fang T, McCaul N, Pinney W 3rd, Sugito HR, Rossotti MA, Gonzalez-Sapienza G, Ploegh HL. Nat Biomed Eng. 2021 Nov;5(11):1389-1401.
● “Sortase-Mediated Phage Decoration for Analytical Applications” (2021) Yuan Ding, He Chen, Jiao Li, Lianrun Huang, Guangyue Song, Zhenfeng Li, Xiude Hua, Gualberto Gonzalez-Sapienza, Bruce D Hammock, Minghua Wang. Analytical Chemistry 93:11800-11808.
● “Ultrastructural characterization of the tegument in protoscoleces of Echinococcus ortleppi” (2021) Miles S, Magnone J, García-Luna J, Ancarola ME, Cucher M, Dematteis S, Frischknecht F, Cyrklaff M, Mourglia-Ettlin G. International Journal for Parasitology 30:S0020-7519(21)00212-5.
● “Robert Braidwood (Bob) Sim. 1951-2021: A Disciple’s Perspective” (2021) Díaz Á. Viruses. 13:1111.
● “Inhibition of inflammatory cytokine production and proliferation in macrophages by Kunitz-type inhibitors from Echinococcus granulosus” (2021) Sagasti C, Casaravilla C, Fernández C, Fló M, Díaz Á. Molecular and Biochemical Parasitology 242:111351.
● “Polyreactive antibodies as potential humoral biomarkers of host resistance to cystic echinococcosis” (2021) García-Luna J, Magnone J, Miles S, López-Santurio C, Dematteis S, Mourglia-Ettlin G. Parasite Immunology 43:e12802.
● “Immune profiling of breast milk from mothers with treated celiac disease” (2020) Villamil E, Rodríguez-Camejo C, Puyol A, Fazio L, Colistro V, Hernández A. Pediatric Research 89:488-495.
2020
● “A nanobody-based test for highly sensitive detection of hemoglobin in fecal samples” (2020) Delfín-Riela T, Rossotti MA, Echaides C, González-Sapienza G. Analytical and Bioanalytical Chemistry 412 :389-396.
● “A FABP4-PPARγ signaling axis regulates human monocyte responses to electrophilic fatty acid nitroalkenes” (2020) Lamas Bervejillo M, Bonanata J, Franchini GR, Richeri A, Marqués JM, Freeman BA, Schopfer FJ, Coitiño EL, Córsico B, Rubbo H, Ferreira AM. Redox Biology 29:101376.
● “Linking murine resistance to secondary cystic echinococcosis with antibody responses targeting Echinococcus granulosus tegumental antigens” (2020) Miles S, Magnone J, Cyrklaff M, Arbildi P, Frischknecht F, Dematteis S, Mourglia-Ettlin G. Immunobiology. doi: 10.1016/j.imbio.2020.151916.
● “Integrative proteomic and glycoproteomic profiling of Mycobacterium tuberculosis culture filtrate” (2020) Tucci P, Portela M, Chetto CR, González-Sapienza G, Marín M. PLoS One.15:e0221837. doi: 10.1371/journal.pone.0221837.
● “Impact of Holder pasteurization on immunological properties of human breast milk over the first year of lactation” (2020) Rodríguez-Camejo C, Puyol A, Fazio L, Villamil E, Arbildi P, Sóñora C, Castro M, Carroscia L, Hernández A. Pediatric Research 87(1):32-41.
● “High-pressure homogenization and high hydrostatic pressure processing of human milk: Preservation of immunological components for human milk banks” (2020) Irazusta A, Rodríguez-Camejo C, Jorcin S, Puyol A, Fazio L, Arias F, Castro M, Hernández A, López-Pedemonte T. Journal of Dairy Science. 103(7):5978-5991.
● “Activation of the NLRP3 inflammasome by particles from the Echinococcus granulosus laminated layer” (2020) Casaravilla C, Pittini Á, Rückerl D, Allen JE, Díaz Á. Infection and Immunity 88: e00190-20.
● “Interactome analysis of CD5 and CD6 ectodomains with tegumental antigens from the helminth parasite Echinococcus granulosus sensu lato” (2020) Miles S, Velasco-de-Andrés M, Lozano F, Mourglia-Ettlin G. International Journal of Biological Macromolecules S0141-8130: 34317-8.
● “The lymphocytic scavenger receptor CD5 shows therapeutic potential in mouse models of fungal infection” (2020) Velasco-de Andrés M, Català C, Casadó-Llombart S, Martínez-Florensa M, Simões I, García-Luna J, Mourglia-Ettlin G, Zaragoza Ó, Carreras E, Lozano F. Antimicrobial Agents and Chemotherapy 65:e01103-20. doi: 10.1128/AAC.01103-20.
● “Proteomic analysis of plasma exosomes from Cystic Echinococcosis patients provides in vivo support for distinct immune response profiles in active vs inactive infection and suggests potential biomarkers” (2020) Fratini F, Tamarozzi F, Macchia G, Bertuccini L, Mariconti M, Birago C, Iriarte A, Brunetti E, Cretu CM, Akhan O, Siles-Lucas M, Díaz A, Casulli A.. PLoS Neglected Tropical Diseases 14: e0008586.
● “Serum amyloid A is a positive acute phase protein in Russian sturgeon challenged with Aeromonas hydrophila” (2020) Castellano M, Silva-Álvarez V, Aversa-Marnai M, Lamas-Bervejillo M, Quartiani I, Perretta A, Villarino A, Ferreira AM. Scientific Reports 10:22162. doi: 10.1038/s41598-020-79065-9.
● “Highly Sensitive Detection of Zika Virus Nonstructural Protein 1 in Serum Samples by a Two-Site Nanobody ELISA” (2020) Delfin-Riela T, Rossotti M, Alvez-Rosado R, Leizagoyen C, González-Sapienza G. Biomolecules 10:1652.
2019
● “Combining proteomics and bioinformatics to explore novel tegumental antigens as vaccine candidates against Echinococcus granulosus” Miles S, Portela M, Cyrklaff M, Ancarola ME, Frischknecht F, Durán R, Dematteis S, Mourglia-Ettlin G. (2019) J Cell Biochem.
● “Understanding Peroxisome Proliferator-Activated Receptors: From the Structure to the Regulatory Actions on Metabolism” (2019) Lamas-Bervejillo M, Ferreira AM. Advances in Experimental Medicine and Biology 1127:39-57. doi: 10.1007/978-3-030-11488-6_3.
● “Inefficient and abortive classical complement pathway activation by the calcium inositol hexakisphosphate component of the Echinococcus granulosus laminated layer” (2019) Barrios AA, Grezzi L, Miles S, Mariconti M, Mourglia-Ettlin G, Seoane PI, Díaz A*. Immunobiology.
● “Impact of Holder pasteurization on immunological properties of human breast milk over the first year of lactation” (2019) Rodríguez-Camejo C, Puyol A, Fazio L, Villamil E, Arbildi P, Sóñora C, Castro M, Carroscia L, Hernández A. (2019) Pediatr Research doi: 10.1038/s41390-019-0500-y.
● “Identification of novel biomarkers asscociated with infection and chronic stress in Russian sturgeon” (2019). Castellano M, Silva-Álvarez V, Aversa M, Costábile A, Quartiani I, Conijeski D, Perretta A, Villarino A, Ferreira AM. Fish & Shellfish Immunology 91:471.
● “Echinococcus granulosus: Insights into the protoscolex F-actin cytoskeleton” (2019) La-Rocca S, Farías J, Chalar C, Kun AE, Fernández V. Acta Tropica doi: 10.1016/j.actatropica.2019.105122.
● “Chronotype-dependent changes in sleep habits associated with dim light melatonin onset in the Antarctic summer” (2019) Silva A, Simón D, Pannunzio B, Casaravilla C, Díaz Á, Tassino B*. Clocks and Sleep.
● “Particles from the Echinococcus granulosus laminated layer inhibit CD40 upregulation in dendritic cells by interfering with Akt activation” (2019) Pittini Á, Martínez-Acosta Y, Casaravilla C, Seoane PI, Rückerl D, Quijano C, Allen JE & Díaz A*. Infection and Immunity. 87: e00641-19.
● “Fluorescent “Turn off-on” Small-Molecule-Monitoring Nanoplatform Based on Dendrimer-like Peptides as Competitors” (2019) Chen H, Ding Y, Yang Q, Barnych B, González-Sapienza G, Hammock BD, Wang M, Hua X. ACS Applied Materials and Interfaces. 11(36):33380-33389.
● “Combined Danio rerio embryo morbidity, mortality and photomotor response assay: A tool for developmental risk assessment from chronic cyanoHAB exposure” (2019) Roegner A, Truong L, Weirich C, Pírez-Schirmer M, Brena B, Miller TR, Tanguay R. Science of the Total Environment.
2018
● “Ageing impairs parasite-specific antibody responses in cystic echinococcosis” (2018) Mourglia-Ettlin G, Miles S, Hernández A, Dematteis S. Parasite Immunology 40(1).
● “Antibody Profile of Colostrum and the Effect of Processing in Human Milk Banks: Implications in Immunoregulatory Properties” (2018) Rodríguez-Camejo C, Puyol A, Fazio L, Rodríguez A, Villamil E, Andina E, Cordobez V, Díaz H, Lemos M, Siré G, Carroscia L, Castro M, Panizzolo L, Hernández A. Journal of Human Lactation. 34(1):137-147.
● “Characterization of catalytic and non-catalytic activities of EgGST2-3, a heterodimeric glutathione transferase from Echinococcus granulosus” (2018) López-González V, La-Rocca S, Arbildi P, Fernández V. Acta Tropica. doi: 10.1016/j.actatropica.2018.01.007.
● “Recombinant Peptidomimetic-Nano Luciferase Tracers for Sensitive Single-Step Immunodetection of Small Molecules” (2018) Ding Y, Hua X, Chen H, Liu F, González-Sapienza G, Wang M. Analytical Chemistry 2018 90(3):2230-2237.
● “In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation” (2018) Villacorta L, Minarrieta L, Salvatore SR, Khoo NK, Rom O, Gao Z, Berman RC, Jobbagy S, Li L, Woodcock SR, Chen YE, Freeman BA, Ferreira AM, Schopfer FJ, Vitturi DA. Redox Biology. 15:522-531
● “Kinesin 1 regulates cilia length through an interaction with the Bardet-Biedl syndrome related protein CCDC28B” (2018) Novas R, Cárdenas-Rodríguez M, Lepanto P, Fabregat M, Rodao M, Fariello MI, Ramos M, Davison C, Casanova G, Alfaya L, Lecumberry F, González-Sapienza G, Irigoín F, Badano JL. Scientific Reports 8:3019.
● “Granulomatous responses in larval taeniid infections” (2018) Álvaro Díaz*, Camila Sagasti, Cecilia Casaravilla Parasite Immunology. doi: 10.1111/pim.12523. [Epub ahead of print].
● “Alternative RNA splicing of leukocyte tissue transglutaminase in celiac disease” (2018) Hernández A, Arbildi P, Sóñora C, Del Río N, Marques JM. Scandinavian Journal of Immunololgy. [Epub ahead of print] doi: 10.1111/sji.12659.
● “Noncompetitive Homogeneous Detection of Small Molecules Using Synthetic Nanopeptamer-Based Luminescent Oxygen Channeling” (2018) Lassabe G, Kramer K, Hammock BD, González-Sapienza G, González-Techera A. Analytical Chemistry.
● “Antigen B from Echinococcus granulosus is a novel ligand for C-reactive protein” (2018) Silva-Álvarez V, Ramos AL, Folle AM, Lagos S, Dee VM, Ferreira AM. Parasite Immunology 40:e12575 doi: 10.1111/pim.12575.
● “Structure and specificity of several triclocarban-binding single domain camelid antibody fragments” (2018) Tabares-da Rosa S, Wogulis LA, Wogulis MD, González-Sapienza G, Wilson DK. Journal of Molecular Recognition. doi: 10.1002/jmr.2755. [Epub ahead of print].
● “Hematobin is a novel immunomodulatory protein from the saliva of the horn fly Haematobia irritans that inhibits the inflammatory response in murine macrophages” (2018) Breijo M, Esteves E, Bizzarro B, Lara PG, Assis JB, Rocha S, Pastro L, Fernández C, Meikle A, Sá-Nunes. (2018) Parasites and Vectors. 11: 435.
● “Quillaja brasiliensis saponin-based nanoparticulate adjuvants are capable of triggering early immune responses” (2018) Cibulski SP, Rivera-Patrón M, Mourglia-Ettlin G, Casaravilla C, Yendo ACA, Fett-Neto AG, Chabalgoity JA, Moreno M, Roehe PM, Silveira F. Scientific Reports 8:13582.
● “Recombinant, Fluorescent, Peptidomimetic Tracer for Immunodetection of Imidaclothiz” (2018) Ding Y, Hua X, Du M, Yang Q, Hou L, Wang L, Liu F, González-Sapienza G, Wang M. Analytical Chemistry. 90:13996-14002.
● “The ectodomains of the lymphocyte scavenger receptors CD5 and CD6 interact with tegumental antigens from Echinococcus granulosus sensu lato and protect mice against secondary cystic echinococcosis” (2018) Mourglia-Ettlin G, Miles S, Velasco-De-Andrés M, Armiger-Borràs N, Cucher M, Dematteis S, Lozano F. PLoS Neglected Tropical Diseases (11):e0006891. doi: 10.1371/journal.pntd.0006891.