{"id":8318,"date":"2022-03-17T09:22:04","date_gmt":"2022-03-17T12:22:04","guid":{"rendered":"https:\/\/higiene.edu.uy\/desarrollo-biotecnologico\/?page_id=8318"},"modified":"2025-01-14T17:50:32","modified_gmt":"2025-01-14T20:50:32","slug":"lineas-de-investigacion","status":"publish","type":"page","link":"https:\/\/higiene.edu.uy\/desarrollo-biotecnologico\/lineas-de-investigacion\/","title":{"rendered":"L\u00edneas de Investigaci\u00f3n"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"8318\" class=\"elementor elementor-8318\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1e0fe05 elementor-section-full_width elementor-section-stretched elementor-section-height-default elementor-section-height-default\" data-id=\"1e0fe05\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-69932aa\" data-id=\"69932aa\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4be1c87 edubin-nav-menu-breakpoint-big-tablet elementor-widget elementor-widget-edubin-header-menu\" data-id=\"4be1c87\" data-element_type=\"widget\" data-widget_type=\"edubin-header-menu.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"edubin-nav-menu-wrapper edubin-header-area edubin-navbar-expand-lg edubin-elementor-nav-menu-wrapper\"><nav class=\"main-navigation edubin-navbar-collapse edubin-elementor-nav\"><ul id=\"menu-1-4be1c87\" class=\"edubin-navbar-nav edubin-navbar-right nav-menu edubin-nav-ul-wrapper\"><li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" id=\"menu-item-8659\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8659\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/\">Inicio<\/a><\/li>\n<li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" id=\"menu-item-8319\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8319\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/integrantes\">Integrantes<\/a><\/li>\n<li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" id=\"menu-item-8585\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8585\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/cursos\">Cursos<\/a><\/li>\n<li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" id=\"menu-item-8586\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8586\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/lineas-de-investigacion\">L\u00edneas de Investigaci\u00f3n<\/a><\/li>\n<li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" id=\"menu-item-8644\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8644\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/proyectos\">Proyectos<\/a><\/li>\n<li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" id=\"menu-item-8582\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8582\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/produccion-cientifica\">Producci\u00f3n cient\u00edfica<\/a><\/li>\n<li itemscope=\"itemscope\" 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512;\" xml:space=\"preserve\"><style type=\"text\/css\">\t.st0{fill:#FFFFFF;}<\/style><path class=\"st0\" d=\"M0,96c0-17.7,14.3-32,32-32h384c17.7,0,32,14.3,32,32s-14.3,32-32,32H32C14.3,128,0,113.7,0,96z M0,256 c0-17.7,14.3-32,32-32h384c17.7,0,32,14.3,32,32s-14.3,32-32,32H32C14.3,288,0,273.7,0,256z M448,416c0,17.7-14.3,32-32,32H32 c-17.7,0-32-14.3-32-32s14.3-32,32-32h384C433.7,384,448,398.3,448,416z\"><\/path><\/svg><\/a><\/div><div class=\"edubin-mobile-menu-nav-wrapper edubin-elementor-mobile-menu-nav-wrapper\"><div class=\"edubin-elementor-mobile-menu-close\"><a href=\"javascript:void(0);\"><i aria-hidden=\"true\" class=\"flaticon-cancel\"><\/i><\/a><\/div><ul id=\"edubin-elementor-mobile-menu-item\" class=\"edubin-elementor-mobile-menu-item\"><li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8659\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/\">Inicio<\/a><\/li>\n<li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8319\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/integrantes\">Integrantes<\/a><\/li>\n<li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8585\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/cursos\">Cursos<\/a><\/li>\n<li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8586\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/lineas-de-investigacion\">L\u00edneas de Investigaci\u00f3n<\/a><\/li>\n<li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8644\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/proyectos\">Proyectos<\/a><\/li>\n<li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8582\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/produccion-cientifica\">Producci\u00f3n cient\u00edfica<\/a><\/li>\n<li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8583\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/extension\">Extensi\u00f3n<\/a><\/li>\n<li itemscope=\"itemscope\" itemtype=\"https:\/\/www.schema.org\/SiteNavigationElement\" class=\"menu-item menu-item-type-custom menu-item-object-custom nav-item menu-item-8581\"><a class=\"nav-link\" href=\"\/desarrollo-biotecnologico\/links-de-interes\">Links de inter\u00e9s<\/a><\/li>\n<\/ul><\/div><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-64199c1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"64199c1\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d5f7e7e\" data-id=\"d5f7e7e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4160a3d elementor-widget elementor-widget-spacer\" data-id=\"4160a3d\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f407786 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f407786\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2849b60\" data-id=\"2849b60\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-47c2113 elementor-widget elementor-widget-custom-title-addons\" data-id=\"47c2113\" data-element_type=\"widget\" data-widget_type=\"custom-title-addons.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"tpc-double_heading\"><div class=\"dbl__subtitle\"><span>L\u00cdNEAS DE INVESTIGACI\u00d3N<\/span><\/div><h3 class=\"dbl__title-wrapper\"><span class=\"dbl__title dbl-title_1\">Unidad Acad\u00e9mica de Desarrollo Biotecnol\u00f3gico<\/span><\/h3><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-89ae9f6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"89ae9f6\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a251c6c\" data-id=\"a251c6c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1c0110d elementor-widget elementor-widget-spacer\" data-id=\"1c0110d\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1db8a44 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1db8a44\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e18d658\" data-id=\"e18d658\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-69536f2 elementor-widget elementor-widget-text-editor\" data-id=\"69536f2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>El Departamento de Desarrollo Biotecnol\u00f3gico se enfoca en la investigaci\u00f3n en biotecnolog\u00edas biom\u00e9dicas dirigidas al desarrollo de productos de aplicaci\u00f3n en salud humana y animal. Para ello, se integra por equipos multidisciplinarios que combinan la capacidad de llevar a cabo investigaci\u00f3n fundamental en \u00e1reas como inmunolog\u00eda, microbiolog\u00eda, biolog\u00eda molecular, bioinform\u00e1tica, con la capacidad para incursionar en \u00e1reas aplicadas. Para concretar nuevos desarrollos tiene como orientaci\u00f3n central adem\u00e1s, vincular las l\u00edneas de investigaci\u00f3n b\u00e1sica con proyectos de interacci\u00f3n con la industria biotecnol\u00f3gica del \u00e1rea.<\/p><p>Actualmente, sus integrantes llevan adelante las siguientes l\u00edneas de investigaci\u00f3n:<\/p><ul><li>Salmonella como vector de antigenos heterologos para el desarrollo de nuevas vacunas.<\/li><li>Uso de Salmonella como base para el desarrollo de inmunoterapias para el c\u00e1ncer.<\/li><li>Desarrollo y validacion de vacunas veterinarias.<\/li><li>Inmunidad entrenada para el desarrollo de inmunoterapias.<\/li><li>Estudio de la variabilidad gen\u00e9tica, patogenicidad y epidemiolog\u00eda de Salmonella no-tifoidea<\/li><li>Gen\u00f3mica Evolutiva y Funcional de Platelmintos y de Pat\u00f3genos Bacterianos.<\/li><li>Salmonella como vector transmitido por alimentos.<\/li><li>Caracterizaci\u00f3n de los venenos of\u00eddicos nacionales.<\/li><li>Desarrollo y evaluaci\u00f3n de nanoadyuvantes tipo ISCOMs e ISCOM-matrices, de fabricaci\u00f3n propia, basados en saponinas deQuillaja brasiliensis de la flora nativa.<\/li><li>Formulaci\u00f3n y evaluaci\u00f3n de vacunas experimentales utilizando ant\u00edgenos de virus respiratorios (influenza y SARS-CoV-2) adyuvadas con ISCOM-matrices en modelos precl\u00ednicos.<\/li><li>Manejo de modelos animales de poblaciones vulnerables como ratones envejecidos e inmunosuprimidos.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-fe89d2c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"fe89d2c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e286bc3\" data-id=\"e286bc3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cb5a6f4 elementor-widget elementor-widget-spacer\" data-id=\"cb5a6f4\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Inicio Integrantes Cursos L\u00edneas de Investigaci\u00f3n Proyectos Producci\u00f3n cient\u00edfica Extensi\u00f3n Links de inter\u00e9s Inicio Integrantes Cursos L\u00edneas de Investigaci\u00f3n Proyectos&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-8318","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/higiene.edu.uy\/desarrollo-biotecnologico\/wp-json\/wp\/v2\/pages\/8318","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/higiene.edu.uy\/desarrollo-biotecnologico\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/higiene.edu.uy\/desarrollo-biotecnologico\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/higiene.edu.uy\/desarrollo-biotecnologico\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/higiene.edu.uy\/desarrollo-biotecnologico\/wp-json\/wp\/v2\/comments?post=8318"}],"version-history":[{"count":51,"href":"https:\/\/higiene.edu.uy\/desarrollo-biotecnologico\/wp-json\/wp\/v2\/pages\/8318\/revisions"}],"predecessor-version":[{"id":9334,"href":"https:\/\/higiene.edu.uy\/desarrollo-biotecnologico\/wp-json\/wp\/v2\/pages\/8318\/revisions\/9334"}],"wp:attachment":[{"href":"https:\/\/higiene.edu.uy\/desarrollo-biotecnologico\/wp-json\/wp\/v2\/media?parent=8318"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}