The global distribution of the toxic cyanobacterium cause negative ecological and health impacts. In that sense, the aim of my work is elucidate the biological and ecological role of toxins production in cyanobacterias.

Based on an evolutionary, genomics, metagenomics and transcriptomics aporach, we evaluate the possible mechanisms involved in toxin production by a cyanobacteria of the genus Raphidiopsis (ex Cylindrospemopsis). Furthermore, we aslo inlcude the study of the bacterial microbiome associated with cyanobacteria,since it has recently been propoused that it would be necessary in the biology of cyanobacteria

Selected publications

• Paula Vico; Sylvia Bonilla; Bruno Cremella; Luis Aubriot; Andres Iriarte; Claudia Piccini. 2020. Título“ Biogeography of the cyanobacterium Raphidiopsis (Cylindrospermopsis) raciborskii: Integrating genomics,phylogenetic and toxicity data”. Molecular Phylogenetics and Evolution 149 (2020) 106824. doi: 10.1016/j.ympev.2020.106824

• Paula Vico; Luis Aubriot; Fatima Martigani; Natalia Rigamonti; Sylvia Bonilla; ClaudiaPiccini. 2016. Título “Influence of nitrogen availability on the expression of genesinvolved in the biosynthesis of saxitoxin and analogs in Cylindrospermopsis raciborskii”. Harmful Algae 56 (2016) 37–43. doi: dx.doi.org/10.1016/j.hal.2016.04.008

• Guadalupe Beamud; Paula Vico; Signe Haakonsson; Gabriela Martınez de la Escalera; Claudia Piccini; Beatriz M. Brena; Macarena Pirez; Sylvia Bonilla. Influence of UV-B radiation on the fitness and toxin expression of the cyanobacterium Cylindrospermopsis raciborskii Hydrobiologia (2016) 763-161. doi:

• Carla Kruk; Angel Segura; LucíaNogueira; Carmela Carballo; Gabriela Martínez de la Escalera; Danilo Calliari; Graciela Ferrari; Macarena Simoens; Jacqueline Cea; Ignacio Alcántara; Paula Vico; Diana Míguez; Claudia Piccini. 2015. Título: “Herramientas para el monitoreo y sistema de alerta de floraciones de cianobacterias nocivas: Río Uruguay y Río de la Plata”. INNOTEC 10 (2015) 23 – 39. doi: